Click on the image to see a larger version. Selected References These references are in PubMed. This may not be the complete list of references from this article. Arch Ophthalmol. A tropical dystrophy.
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Abstract Keywords : Climatic droplet keratopathy CDK , alternatively known as oil droplet keratopathy, is an acquired corneal degenerative disorder that usually initiates at the limbus and extends towards the visual axis in the interpalpebral area causing irritation, irregularity and thinning of the corneal surface associated with visual deterioration.
Clumps of variably sized golden-yellow globules accumulate in the superficial corneal stroma and are derived from photochemical degradation of plasma proteins by U.
V light, which is considered the chief etio-pathogenetic factor. Our patient was a 70 year old farmer who presented with immature senile cataract Nuclear sclerosis grade III in the left eye and underwent conventional extra-capsular cataract extraction with intraocular lens implantation under guarded visual prognosis in view of poor media clarity subsequent to grade 3 CDK.
The central cornea in this eye subsequently developed a persistent non healing epithelial defect in the area involved by CDK. Temporary tarsorraphy was performed along-with lubricant supplementation. The right eye was pseudophakic, with a visual acuity of hand motions close to face, with post penetrating keratoplasty PK glaucomatous optic atrophy and CDK involving the graft host junction.
PK was done elsewhere for extensive CDK involving the visual axis. Penetrating and lamellar keratoplasty has subsequent risk of long term complications including graft rejection and infections, however, it is the only treatment option in advanced cases. Amniotic membrane transplant may serve as a favorable treatment modality to aid in ocular surface reconstruction.
Satisfactory ambulatory vision after cataract surgery averted the need for a subsequent surgery in the form of PK as done in the other eye. In vivo confocal microscopy study of climatic droplet keratopathy. Eye Lond Engl ; —3. Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy. Cornea ; —4. Amniotic membrane transplant with superficial keratectomy in superficial corneal degenerations: efficacy in a rural population of north India.
Indian J Ophthalmol ; — Article Options.
Aetiology of climatic droplet keratopathy and pterygium.
Surv Ophthalmol. Climatic droplet keratopathy. Climatic droplet keratopathy CDK is a degenerative condition characterized by the accumulation of translucent material in the superficial corneal stroma within the interpalpebral strip, beginning peripherally and spreading centrally. Progressive accumulation in later life can lead to significant visual disability, and people leading an outdoor life are particularly at risk. The translucent corneal deposits are composed of protein, but although they share some of the staining characteristics of degenerated protein, such as that found in pingueculae, their exact histochemical nature remains uncertain. The corneal deposits are thought to be derived from plasma proteins, which diffuse into the normal cornea, and may be photochemically degraded by excessive exposure to ultra-violet light UV.
Climatic droplet keratopathy.
Climatic droplet keratopathy, exfoliation syndrome, and cataract.